Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 1.00 |
| ▸ | GAA | P10253 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.62 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.62 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13287459 | 0.98 | HPGD (0.97) | HPGDGAALMNAKDM4EL3MBTL1 | |
| SCHEMBL5933901 | 0.98 | HPGD (0.97) | HPGDGAALMNAKDM4EL3MBTL1 | |
| SCHEMBL1093862 | 0.95 | HPGD (0.91) | HPGDGAALMNAKDM4EL3MBTL1 | |
| SCHEMBL27381884 | 0.91 | HPGD (0.83) | HPGDLMNAL3MBTL1HDAC3TSHR | |
| SCHEMBL11367962 | 0.90 | HPGD (0.82) | HPGDGAA | |
| SCHEMBL8744900 | 0.90 | HPGD (0.81) | HPGDGAALMNAKDM4EL3MBTL1 | |
| SCHEMBL27404704 | 0.89 | HPGD (0.80) | HPGDGAALMNAKDM4EL3MBTL1 | |
| SCHEMBL6360887 | 0.88 | HPGD (0.79) | HPGDGAALMNAKDM4EL3MBTL1 | |
| SCHEMBL7426779 | 0.87 | EPHX2 (0.78) | HPGDHDAC3EPHX2HDAC1HDAC2 | |
| SCHEMBL15598268 | 0.87 | HPGD (0.77) | HPGDGAALMNAKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2342180-A2 | ORGANIC COMPOUNDS SUITABLE FOR MODULATING FRAGRANCE COMPOSITIONS | Givaudan SA (CH) | 2011-07-13 | — | — | EP | disclosed |
| CN-101198377-B | Cosmetic composition for removing spots or whitening skin containing at least one oxazoline as active ingredient | EXPANSCIENCE LAB | 2011-01-05 | — | — | CN | disclosed |
| WO-2010037244-A2 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2010-04-08 | — | — | WO | disclosed |
| CN-101198377-A | Cosmetic composition for removing spots or whitening skin containing at least one oxazoline as active ingredient | EXPANSCIENCE LAB (FR) | 2008-06-11 | — | — | CN | disclosed |