Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.81 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.77 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.71 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.71 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.71 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.71 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.71 |
| ▸ | TSHR | P16473 | 1/20 | 0.71 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.70 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.68 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 2/20 | 0.68 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.66 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.66 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.66 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2101709 | 0.93 | LMNA (0.77) | HPGDL3MBTL1LMNAKDM4EHDAC2 | |
| SCHEMBL17589255 | 0.93 | HPGD (0.72) | HPGDL3MBTL1LMNAKDM4EHDAC2 | |
| SCHEMBL5933901 | 0.92 | HPGD (0.97) | HPGDL3MBTL1LMNAKDM4EHDAC2 | |
| SCHEMBL13287459 | 0.92 | HPGD (0.97) | HPGDL3MBTL1LMNAKDM4EHDAC2 | |
| SCHEMBL7778138 | 0.91 | HPGD (0.74) | HPGDL3MBTL1LMNAKDM4EHDAC2 | |
| Hydrochloric Acid SCHEMBL7769509 | 0.91 | HPGD (0.68) | HPGDL3MBTL1LMNAKDM4EHDAC2 | |
| SCHEMBL1233731 | 0.91 | HDAC1 (0.83) | HPGDL3MBTL1LMNAHDAC2HDAC8 | |
| SCHEMBL20385912 | 0.90 | HPGD (0.72) | HPGDL3MBTL1LMNAKDM4EHDAC2 | |
| SCHEMBL2187602 | 0.90 | HPGD (1.00) | HPGDL3MBTL1LMNAKDM4EHDAC2 | |
| SCHEMBL6289079 | 0.89 | L3MBTL1 (0.72) | HPGDL3MBTL1LMNAKDM4EHDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754693-A2 | Novel aminophenylphosphonic acid derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-01-22 | — | — | EP | disclosed |