SCHEMBL21877489

SCHEMBL21877489

CC1(C)CC(=O)C=C(/C=C/c2ccccc2)C1

nearest known ligand 0.60

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.60
MEN1 O00255 4/20 0.60
KMT2A Q03164 4/20 0.60
NPC1 O15118 3/20 0.50
RAB9A P51151 2/20 0.50
APEX1 P27695 1/20 0.45
HPGD P15428 4/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
LMNA P02545 1/20 0.42
PKM P14618 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.40
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C19 P33261 1/20 0.39
SRD5A1 P18405 2/20 0.38
SRD5A2 P31213 2/20 0.38
MAPT P10636 2/20 0.38
NPSR1 Q6W5P4 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28360134 1.00 ALDH1A1 (0.60) ALDH1A1MEN1KMT2ANPC1RAB9A
SCHEMBL13902572 0.91 ALDH1A1 (0.66) ALDH1A1MEN1KMT2ANPC1RAB9A
SCHEMBL13852334 0.87 MEN1 (0.54) ALDH1A1MEN1KMT2ANPC1RAB9A
SCHEMBL28363755 0.85 ALDH1A1 (0.58) ALDH1A1MEN1KMT2ANPC1RAB9A
SCHEMBL28363756 0.85 ALDH1A1 (0.58) ALDH1A1MEN1KMT2ANPC1RAB9A
SCHEMBL28363903 0.83 KMT2A (0.57) ALDH1A1MEN1KMT2ANPC1RAB9A
SCHEMBL28360495 0.83 ALDH1A1 (0.57) ALDH1A1MEN1KMT2ANPC1RAB9A
SCHEMBL28360494 0.83 ALDH1A1 (0.57) ALDH1A1MEN1KMT2ANPC1RAB9A
SCHEMBL28360339 0.83 ALDH1A1 (0.57) ALDH1A1MEN1KMT2ANPC1RAB9A
SCHEMBL28498837 0.83 ALDH1A1 (0.57) ALDH1A1MEN1KMT2ANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110668950-B Chiral delta-nitroketene compound and asymmetric synthesis method and application thereof 浙江工业大学 2023-03-31 CN disclosed
CN-112047905-A Method for synthesizing 1, 5-diketone compound by air oxidation of dienone 浙江工业大学 2020-12-08 CN disclosed
WO-2020055129-A1 COMPOSITION FOR TREATING OR PREVENTING CANCER COMPRISING VERBENONE DERIVATIVE 고려대학교 산학협력단 2020-03-19 WO disclosed
CN-110668950-A Chiral delta-nitroketene compound and asymmetric synthesis method and application thereof 浙江工业大学 2020-01-10 CN disclosed