SCHEMBL21878562

SCHEMBL21878562

CN=c1ccc2c(-c3ccc(N)cc3C(=O)O)c3ccc(NC)cc3oc-2c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ USP2 O75604 3/20 0.56
▸ L3MBTL1 Q9Y468 1/20 0.56
▸ ABCB1 P08183 1/20 0.46
▸ CFTR P13569 1/20 0.44
▸ PAX8 Q06710 1/20 0.44
▸ ATM Q13315 1/20 0.44
▸ GOPC Q9HD26 1/20 0.44
▸ CA9 Q16790 15/20 0.41
▸ CA1 P00915 13/20 0.41
▸ CA2 P00918 13/20 0.41
▸ CA12 O43570 5/20 0.40
▸ MEN1 O00255 1/20 0.39
▸ ALPL P05186 1/20 0.39
▸ POLB P06746 1/20 0.39
▸ ALPI P09923 1/20 0.39
▸ ALPG P10696 1/20 0.39
▸ KMT2A Q03164 1/20 0.39
▸ CA14 Q9ULX7 2/20 0.38
▸ DNASE1L3 Q13609 1/20 0.37
▸ PRMT1 Q99873 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21878561 1.00 USP2 (0.56) USP2L3MBTL1ABCB1CFTRPAX8
SCHEMBL30414772 0.90 USP2 (0.45) USP2L3MBTL1ABCB1CFTRPAX8
SCHEMBL6056016 0.88 ABCB1 (0.45) USP2L3MBTL1ABCB1CFTRPAX8
SCHEMBL12697372 0.88 ABCB1 (0.45) USP2L3MBTL1ABCB1CFTRPAX8
SCHEMBL609855 0.88 ABCB1 (0.45) USP2L3MBTL1ABCB1CFTRPAX8
Perchlorate SCHEMBL5606712 0.84 ABCB1 (0.42) USP2L3MBTL1ABCB1CFTRPAX8
Perchlorate SCHEMBL29692775 0.84 ABCB1 (0.42) USP2L3MBTL1ABCB1CFTRPAX8
Perchlorate SCHEMBL5606714 0.84 ABCB1 (0.42) USP2L3MBTL1ABCB1CFTRPAX8
SCHEMBL14611311 0.84 ABCB1 (0.58) USP2L3MBTL1ABCB1CFTRPAX8
SCHEMBL24621980 0.81 DNASE1L3 (0.40) USP2L3MBTL1ABCB1CA9CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11649228-B2 Zinc indicators for cellular imaging THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2023-05-16 — — US disclosed
US-20200131160-A1 ZINC INDICATORS FOR CELLULAR IMAGING NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2020-04-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200131160-A1 ZINC INDICATORS FOR CELLULAR IMAGING IAPP, SLC30A6, SLC30A7 USP2 2054/4885L3MBTL1 2699/4885ABCB1 3916/4885
US-11649228-B2 Zinc indicators for cellular imaging IAPP, SLC30A6, SLC30A7 USP2 2054/4885L3MBTL1 2699/4885ABCB1 3916/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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