Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Perflenapent SCHEMBL5186220 | 0.79 | LMNA (0.47) | LMNAF2PRSS1PRSS2PRSS3 | |
| Perflubutane SCHEMBL5188622 | 0.75 | LMNA (0.41) | LMNAF2PRSS1PRSS2PRSS3 | |
| SCHEMBL1687172 | 0.75 | LMNA (0.38) | LMNAF2PRSS1PRSS2PRSS3 | |
| SCHEMBL6749674 | 0.75 | LMNA (0.38) | LMNAF2PRSS1PRSS2PRSS3 | |
| SCHEMBL1687232 | 0.75 | LMNA (0.38) | LMNAF2PRSS1PRSS2PRSS3 | |
| SCHEMBL1686995 | 0.75 | LMNA (0.38) | LMNAF2PRSS1PRSS2PRSS3 | |
| SCHEMBL1686968 | 0.75 | LMNA (0.38) | LMNAF2PRSS1PRSS2PRSS3 | |
| SCHEMBL1687065 | 0.75 | LMNA (0.38) | LMNAF2PRSS1PRSS2PRSS3 | |
| SCHEMBL6747072 | 0.75 | LMNA (0.38) | LMNAF2PRSS1PRSS2PRSS3 | |
| SCHEMBL1686791 | 0.75 | LMNA (0.38) | LMNAF2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11357619-B2 | Adjustable ophthalmic devices, systems, and methods of adjustment | VERILY LIFE SCIENCES LLC (US) | 2022-06-14 | — | — | US | disclosed |
| CN-112930155-A | Adjustable ophthalmic device, system and adjustment method | 威里利生命科学有限责任公司 | 2021-06-08 | — | — | CN | disclosed |
| US-20200129288-A1 | ADJUSTABLE OPHTHALMIC DEVICES, SYSTEMS, AND METHODS OF ADJUSTMENT | VERILY LIFE SCIENCES LLC | 2020-04-30 | — | — | US | disclosed |