SCHEMBL2187975

SCHEMBL2187975

Brc1ccc2c(c1)C(=C1c3cc(Br)ccc3-c3ccc(Br)cc31)c1cc(Br)ccc1-2

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S100A4 P26447 1/20 0.62
PTPRC P08575 1/20 0.52
BCL2 P10415 2/20 0.45
MCL1 Q07820 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA4 P22748 1/20 0.44
CA7 P43166 1/20 0.44
CA9 Q16790 1/20 0.44
MAPK1 P28482 2/20 0.42
ALDH1A1 P00352 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
CYP2A6 P11509 2/20 0.41
ALOX15 P16050 2/20 0.38
TGM2 P21980 1/20 0.38
CES1 P23141 1/20 0.38
ESR1 P03372 1/20 0.38
ESR2 Q92731 1/20 0.38
AHR P35869 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31016540 1.00 S100A4 (0.62) S100A4PTPRCBCL2MCL1CA1
SCHEMBL13868495 0.89 PTPRC (0.61) S100A4PTPRCBCL2MCL1CA1
SCHEMBL12698905 0.89 PTPRC (0.61) S100A4PTPRCBCL2MCL1CA1
SCHEMBL18470983 0.80 PTPRC (0.52) S100A4PTPRCBCL2MCL1CA1
SCHEMBL7866191 0.79 PTPRC (0.70) S100A4PTPRCBCL2MCL1CA1
SCHEMBL26112719 0.79 PTPRC (0.70) S100A4PTPRCBCL2MCL1CA1
SCHEMBL19091719 0.78 S100A4 (0.52) S100A4PTPRCBCL2MCL1CA1
SCHEMBL8025811 0.77 S100A4 (0.56) S100A4PTPRCBCL2MCL1CA1
SCHEMBL39700 0.77 S100A4 (0.90) S100A4PTPRCBCL2MCL1CA1
SCHEMBL205625 0.77 S100A4 (0.56) S100A4PTPRCBCL2MCL1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016201513-A1 ELECTROACTIVE MATERIALS, PRINTING COMPOSITIONS AND METHODS OF MANUFACTURING SOLAR CELLS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2016-12-22 WO disclosed
WO-2016201513-A1 ELECTROACTIVE MATERIALS, PRINTING COMPOSITIONS AND METHODS OF MANUFACTURING SOLAR CELLS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2016-12-22 WO disclosed
CN-102219656-B Symmetric bifluorenylidene derivative having characteristic of multi-photon absorption, and synthesis method and application thereof UNIV HENAN 2013-03-27 CN disclosed
EP-2342172-B1 BIFLUORENYLIDENE DERIVATIVES, THEIR PREPARATION AND USES THEREOF UNIV ROMA (IT) 2012-08-08 EP disclosed
CN-102219656-A Symmetric bifluorenylidene derivative having characteristic of multi-photon absorption, and synthesis method and application thereof UNIV HENAN 2011-10-19 CN disclosed
EP-2342172-A1 BIFLUORENYLIDENE DERIVATIVES, THEIR PREPARATION AND USES THEREOF Università degli Studi di Roma "La Sapienza" (IT) 2011-07-13 EP disclosed
WO-2010038251-A1 BIFLUORENYLIDENE DERIVATIVES, THEIR PREPARATION AND USES THEREOF UNIVERSITÀ DEGLI STUDI DI ROMA LA SAPIENZA (IT) 2010-04-08 WO disclosed
WO-2010038251-A1 BIFLUORENYLIDENE DERIVATIVES, THEIR PREPARATION AND USES THEREOF UNIVERSITÀ DEGLI STUDI DI ROMA LA SAPIENZA (IT) 2010-04-08 WO disclosed