Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | IDO1 | P14902 | 1/20 | 0.55 |
| ▸ | STAT3 | P40763 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | XBP1 | P17861 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.54 |
| ▸ | UBE2M | P61081 | 1/20 | 0.54 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21880131 | 1.00 | MEN1 (0.59) | MEN1KMT2AALDH1A1CYP1A2POLB | |
| SCHEMBL5019067 | 0.92 | ALDH1A1 (0.53) | MEN1KMT2AALDH1A1CYP1A2POLB | |
| SCHEMBL3277354 | 0.90 | TACR1 (0.60) | POLBMAPT | |
| SCHEMBL3277359 | 0.90 | TACR1 (0.60) | POLBMAPT | |
| SCHEMBL13365288 | 0.88 | MEN1 (0.57) | MEN1KMT2AALDH1A1CYP1A2POLB | |
| SCHEMBL5019032 | 0.88 | MEN1 (0.57) | MEN1KMT2AALDH1A1CYP1A2POLB | |
| SCHEMBL5019122 | 0.88 | MEN1 (0.57) | MEN1KMT2AALDH1A1CYP1A2POLB | |
| SCHEMBL21880197 | 0.85 | MAPT (0.65) | MEN1KMT2AALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL21880198 | 0.85 | MAPT (0.65) | MEN1KMT2AALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL966551 | 0.84 | ALDH1A1 (0.58) | MEN1KMT2AALDH1A1CYP1A2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112601734-B | Oximino naphthoquinone compound and preparation method and application thereof | 普济生物科技（台州）有限公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-112601734-A | Oximido naphthoquinone compound and preparation method and application thereof | 普济生物科技（台州）有限公司 | 2021-04-02 | — | — | CN | disclosed |
| WO-2020082817-A1 | NAPHTHOQUINONE OXIME COMPOUND, PREPARATION METHOD THEREFOR, AND USES THEREOF | 普济生物科技（台州）有限公司 | 2020-04-30 | — | — | WO | disclosed |