Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | LNPEP | Q9UIQ6 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | GPR142 | Q7Z601 | 3/20 | 0.47 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | XIAP | P98170 | 1/20 | 0.45 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.45 |
| ▸ | AKT1 | P31749 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21880144 | 1.00 | THRB (0.51) | THRBLNPEPRAB9AGPR142ERAP2 | |
| SCHEMBL30452301 | 1.00 | THRB (0.51) | THRBLNPEPRAB9AGPR142ERAP2 | |
| SCHEMBL28085732 | 0.87 | THRB (0.66) | THRBLNPEPGPR142MMP2 | |
| SCHEMBL28085741 | 0.84 | THRB (0.55) | THRBRAB9AGPR142MMP2 | |
| SCHEMBL21880156 | 0.84 | SMN1; SMN2 (0.54) | RAB9AGPR142ROCK2ALPIPKM | |
| SCHEMBL28552924 | 0.84 | SMN1; SMN2 (0.54) | RAB9AGPR142ROCK2ALPIPKM | |
| Hydrochloric Acid SCHEMBL23093116 | 0.79 | CA1 (0.48) | LNPEP | |
| Hydrochloric Acid SCHEMBL29715457 | 0.79 | CA1 (0.48) | LNPEP | |
| Hydrochloric Acid SCHEMBL23093114 | 0.79 | CA1 (0.48) | LNPEP | |
| SCHEMBL6719263 | 0.78 | POLB (0.63) | RAB9AALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112601734-B | Oximino naphthoquinone compound and preparation method and application thereof | 普济生物科技（台州）有限公司 | 2023-05-23 | — | — | CN | disclosed |
| WO-2020082817-A1 | NAPHTHOQUINONE OXIME COMPOUND, PREPARATION METHOD THEREFOR, AND USES THEREOF | 普济生物科技（台州）有限公司 | 2020-04-30 | — | — | WO | disclosed |