Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | FASN | P49327 | 3/20 | 0.31 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.30 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.30 |
| ▸ | CFB | P00751 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23676462 | 0.85 | KDM4E (0.36) | KDM4ELMNAHSD17B10ADORA3ADORA2A | |
| SCHEMBL21263286 | 0.80 | PARP1 (0.34) | SCN10AKDM4EHSD17B10ADORA3CSNK1D | |
| SCHEMBL21879803 | 0.79 | CFB (0.40) | SCN10AKDM4ELMNAHSD17B10CFB | |
| SCHEMBL6979886 | 0.79 | KDM4E (0.41) | KDM4ELMNAHSD17B10ADORA3ADORA2A | |
| SCHEMBL22962129 | 0.76 | KDM4E (0.39) | KDM4ELMNAHSD17B10ADORA3ADORA2A | |
| SCHEMBL23676508 | 0.75 | KDM4E (0.35) | SCN10AKDM4ELMNAHSD17B10 | |
| SCHEMBL23676488 | 0.74 | KDM4E (0.41) | KDM4ELMNAHSD17B10ADORA3ADORA2A | |
| SCHEMBL13119215 | 0.72 | KDM4E (0.53) | SCN10AKDM4ELMNAHSD17B10CSNK1D | |
| SCHEMBL23676505 | 0.71 | KDM4E (0.35) | KDM4ELMNAHSD17B10ADORA3ADORA2A | |
| SCHEMBL22962261 | 0.70 | KDM4E (0.50) | SCN10AKDM4ELMNAHSD17B10CSNK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11834462-B2 | Somatostatin modulators and uses thereof | Crinetics Pharmaceuticals, Inc. (US) | 2023-12-05 | — | — | US | disclosed |
| US-20230022513-A1 | SOMATOSTATIN MODULATORS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. | 2023-01-26 | — | — | US | disclosed |
| US-20220048924-A1 | SOMATOSTATIN MODULATORS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. | 2022-02-17 | — | — | US | disclosed |
| US-11186590-B2 | Somatostatin modulators and uses thereof | Crinetics Pharmaceuticals, Inc. (US) | 2021-11-30 | — | — | US | disclosed |
| US-11072598-B2 | Somatostatin modulators and uses thereof | Crinetics Pharmaceuticals, Inc. (US) | 2021-07-27 | — | — | US | disclosed |
| US-20210040087-A1 | SOMATOSTATIN MODULATORS AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2021-02-11 | — | — | US | disclosed |
| US-20200283453-A1 | SOMATOSTATIN MODULATORS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. | 2020-09-10 | — | — | US | disclosed |
| US-10696689-B2 | Somatostatin modulators and uses thereof | Crinetics Pharmaceuticals, Inc. (US) | 2020-06-30 | — | — | US | disclosed |
| US-20200087318-A1 | SOMATOSTATIN MODULATORS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. | 2020-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230022513-A1 | SOMATOSTATIN MODULATORS AND USES THEREOF | SSTR5, SSTR2, SSTR4 | SCN10A 1550/4885KDM4E 4554/4885LMNA 3475/4885 |
| US-20220048924-A1 | SOMATOSTATIN MODULATORS AND USES THEREOF | SSTR5, SSTR2, SSTR4 | SCN10A 1550/4885KDM4E 4554/4885LMNA 3475/4885 |
| US-20200087318-A1 | SOMATOSTATIN MODULATORS AND USES THEREOF | SSTR5, SSTR2, SSTR4 | SCN10A 1550/4885KDM4E 4554/4885LMNA 3475/4885 |
| US-11834462-B2 | Somatostatin modulators and uses thereof | SSTR5, SSTR2, SSTR4 | SCN10A 1550/4885KDM4E 4554/4885LMNA 3475/4885 |
| US-20210040087-A1 | SOMATOSTATIN MODULATORS AND USES THEREOF | SSTR5, SSTR2, SSTR4 | SCN10A 1550/4885KDM4E 4554/4885LMNA 3475/4885 |
| US-20200283453-A1 | SOMATOSTATIN MODULATORS AND USES THEREOF | SSTR5, SSTR2, SSTR4 | SCN10A 1550/4885KDM4E 4554/4885LMNA 3475/4885 |
| US-11186590-B2 | Somatostatin modulators and uses thereof | SSTR5, SSTR2, SSTR4 | SCN10A 1550/4885KDM4E 4554/4885LMNA 3475/4885 |
| US-10696689-B2 | Somatostatin modulators and uses thereof | SSTR5, SSTR2, SSTR4 | SCN10A 1550/4885KDM4E 4554/4885LMNA 3475/4885 |
| US-11072598-B2 | Somatostatin modulators and uses thereof | SSTR5, SSTR2, SSTR4 | SCN10A 1550/4885KDM4E 4554/4885LMNA 3475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.