Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 6/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | TACR2 | P21452 | 3/20 | 0.32 |
| ▸ | CDK4 | P11802 | 1/20 | 0.32 |
| ▸ | CCND1 | P24385 | 1/20 | 0.32 |
| ▸ | MLKL | Q8NB16 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20863650 | 0.84 | KDM4E (0.42) | KDM4ELMNAHSD17B10HRH4ADORA3 | |
| SCHEMBL6979886 | 0.83 | KDM4E (0.41) | KDM4ELMNAHSD17B10HRH4ADORA3 | |
| SCHEMBL13542764 | 0.81 | KDM4E (0.40) | KDM4ELMNAHSD17B10HRH4ADORA3 | |
| SCHEMBL23676488 | 0.78 | KDM4E (0.41) | KDM4ELMNAHSD17B10ADORA3ADORA2A | |
| SCHEMBL23676493 | 0.78 | PDE3B (0.39) | KDM4ELMNAHSD17B10ADORA3ADORA2A | |
| SCHEMBL24122690 | 0.77 | ALDH1A1 (0.44) | KDM4EHRH4ADORA3ARCYP1A2 | |
| SCHEMBL23676462 | 0.76 | KDM4E (0.36) | KDM4ELMNAHSD17B10ADORA3ADORA2A | |
| SCHEMBL21880174 | 0.76 | SCN10A (0.38) | KDM4ELMNAHSD17B10ADORA3ADORA2A | |
| SCHEMBL12309239 | 0.76 | KDM4E (0.45) | KDM4ELMNAHSD17B10ADORA3ADORA2A | |
| SCHEMBL23676505 | 0.74 | KDM4E (0.35) | KDM4ELMNAHSD17B10ADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11072598-B2 | Somatostatin modulators and uses thereof | Crinetics Pharmaceuticals, Inc. (US) | 2021-07-27 | — | — | US | disclosed |
| US-20210040087-A1 | SOMATOSTATIN MODULATORS AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2021-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210040087-A1 | SOMATOSTATIN MODULATORS AND USES THEREOF | SSTR5, SSTR2, SSTR4 | KDM4E 4554/4885LMNA 3475/4885HSD17B10 3787/4885 |
| US-11072598-B2 | Somatostatin modulators and uses thereof | SSTR5, SSTR2, SSTR4 | KDM4E 4554/4885LMNA 3475/4885HSD17B10 3787/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.