Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphine SCHEMBL22345943 | 0.95 | MAPT (0.48) | MAPTLMNAGAAPOLBTDP1 | |
| SCHEMBL27988230 | 0.93 | MAPT (0.49) | MAPTLMNAGAAPOLBTDP1 | |
| SCHEMBL2482229 | 0.84 | MAPT (0.50) | MAPTGAATDP1KMT2AMEN1 | |
| SCHEMBL19512129 | 0.83 | KMT2A (0.45) | MAPTGAAPOLBKMT2AALDH1A1 | |
| SCHEMBL13805553 | 0.82 | TSHR (0.48) | MAPTLMNAGAAPOLBTDP1 | |
| Benzamide SCHEMBL21771939 | 0.82 | PARP10 (0.49) | MAPTLMNAGAAPOLBTDP1 | |
| SCHEMBL11511170 | 0.81 | KMT2A (0.54) | MAPTLMNAGAAPOLBTDP1 | |
| SCHEMBL2481945 | 0.81 | MAPT (0.48) | MAPTLMNAGAATDP1KMT2A | |
| SCHEMBL13104612 | 0.81 | MAPT (0.50) | MAPTLMNAGAAPOLBTDP1 | |
| SCHEMBL14137285 | 0.81 | MAPT (0.48) | MAPTLMNAGAAPOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020082914-A1 | PREPARATION FOR ORGANIC PHOSPHORUS COMPOUND BY CONDENSATION OF MES-TRIMETHYL TRIHALOMETHYL BENZENE AND DIPHENYL PHOSPHINE OXIDE | 深圳有为技术控股集团有限公司 | 2020-04-30 | — | — | WO | claimed |