SCHEMBL21880258

SCHEMBL21880258

COc1ccc(-c2ccc(OC)c(C3(O)c4ccccc4-c4ccccc43)c2)cc1C1(O)c2ccccc2-c2ccccc21

nearest known ligand 0.54

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 17/20 0.54
KMT2A Q03164 1/20 0.42
SIGMAR1 Q99720 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7316250 0.84 KMT2A (0.56) PDK2KMT2ASIGMAR1
SCHEMBL21880259 0.80 PDK2 (0.47) PDK2KMT2A
SCHEMBL7314812 0.77 SCN9A (0.48) PDK2KMT2A
SCHEMBL17533937 0.71 PDK2 (0.48) PDK2
SCHEMBL14970785 0.71 PDK2 (0.36) PDK2KMT2A
SCHEMBL13128125 0.70 PDK2 (1.00) PDK2
SCHEMBL10025087 0.70 PDK2 (0.50) PDK2
SCHEMBL10025096 0.70 PDK2 (0.50) PDK2
SCHEMBL24061736 0.69 PDK2 (0.37) PDK2
SCHEMBL30829201 0.69 PDK2 (0.57) PDK2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210278766-A1 COATING-TYPE COMPOSITION FOR FORMING ORGANIC FILM, PATTERNING PROCESS, POLYMER, AND METHOD FOR MANUFACTURING POLYMER SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-09-09 US disclosed
US-10604618-B2 Compound, method for manufacturing the compound, and composition for forming organic film SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-03-31 US disclosed