SCHEMBL30829201

SCHEMBL30829201

COc1cccc(-c2cc(OC)ccc2C2(O)c3ccccc3-c3ccccc32)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 4/20 0.57
MEN1 O00255 1/20 0.46
GAA P10253 1/20 0.46
KMT2A Q03164 1/20 0.46
CYP1A1 P04798 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2E1 P05181 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2C8 P10632 1/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2A6 P11509 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP4B1 P13584 1/20 0.44
CYP2B6 P20813 1/20 0.44
CYP3A5 P20815 1/20 0.44
CYP2A7 P20853 1/20 0.44
CYP3A7 P24462 1/20 0.44
CYP2F1 P24903 1/20 0.44
CYP2C18 P33260 1/20 0.44
CYP2C19 P33261 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27392537 1.00 PDK2 (0.57) PDK2MEN1GAAKMT2ACYP1A1
SCHEMBL17439398 0.79 PDK2 (0.64) PDK2MEN1GAAKMT2AHDAC4
SCHEMBL7315657 0.78 PDK2 (0.51) PDK2MEN1GAAKMT2AALDH1A1
SCHEMBL17929490 0.78 PDK2 (0.48) PDK2CYP1A1CYP1A2CYP2E1CYP3A4
SCHEMBL2020140 0.77 ABL1 (0.59) GAACYP1A1CYP1A2CYP2E1CYP3A4
SCHEMBL17471968 0.75 PDK2 (0.59) PDK2MEN1GAAKMT2AHDAC4
SCHEMBL26026227 0.75 PDK2 (0.41) PDK2MEN1GAAKMT2AADORA2A
SCHEMBL30829197 0.74 PDK2 (0.66) PDK2MEN1GAAKMT2ACYP1A2
SCHEMBL27392579 0.74 PDK2 (0.66) PDK2MEN1GAAKMT2ACYP1A2
SCHEMBL13211663 0.73 ABL1 (0.60) CYP1A1CYP1A2CYP2E1CYP3A4CYP2C8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024091684-A1 POLYSULFATE AND POLYSULFONATE POLYMERS THE SCRIPPS RESEARCH INSTITUTE (US) 2024-05-02 WO disclosed