Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | ASGR1 | P07306 | 1/20 | 0.31 |
| ▸ | FPR3 | P25089 | 1/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.30 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.30 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26917641 | 0.86 | HDAC6 (0.43) | HDAC6HDAC1HDAC2CA14PDK2 | |
| SCHEMBL8553597 | 0.85 | HDAC6 (0.39) | HDAC6HDAC1HDAC2CA14PDK2 | |
| SCHEMBL12670076 | 0.84 | AAK1 (0.36) | HDAC6HDAC1HDAC2CA14PDK2 | |
| SCHEMBL10260946 | 0.82 | HDAC6 (0.40) | HDAC6HDAC1HDAC2CA14PDK2 | |
| SCHEMBL21203873 | 0.81 | HDAC6 (0.37) | HDAC6HDAC1HDAC2CA14CA12 | |
| SCHEMBL381146 | 0.81 | HDAC6 (0.39) | HDAC6HDAC1HDAC2CA14PDK2 | |
| SCHEMBL22416332 | 0.81 | HDAC6 (0.34) | HDAC6HDAC1HDAC2CA14PDK2 | |
| SCHEMBL19901069 | 0.81 | HDAC6 (0.34) | HDAC6HDAC1HDAC2CA14PDK2 | |
| SCHEMBL15370926 | 0.80 | CA14 (0.39) | HDAC6HDAC1HDAC2CA14CA12 | |
| SCHEMBL5742200 | 0.80 | CA14 (0.39) | HDAC6HDAC1HDAC2CA14ASGR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200115368-A1 | INHIBITING FATTY ACID SYNTHASE (FASN) | FORMA THERAPEUTICS, INC. | 2020-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200115368-A1 | INHIBITING FATTY ACID SYNTHASE (FASN) | FASN, SCD, FADS1 | HDAC6 869/4885HDAC1 883/4885HDAC2 1381/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.