⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17465446 | 0.90 | — | — | |
| SCHEMBL21880466 | 0.86 | HIF1A (0.36) | — | |
| SCHEMBL17453472 | 0.86 | HIF1A (0.36) | — | |
| SCHEMBL19644567 | 0.80 | — | — | |
| SCHEMBL17465454 | 0.78 | — | — | |
| SCHEMBL19962800 | 0.76 | — | — | |
| SCHEMBL20642796 | 0.76 | — | — | |
| SCHEMBL21880509 | 0.74 | — | — | |
| SCHEMBL17453473 | 0.74 | HIF1A (0.36) | — | |
| SCHEMBL17453462 | 0.73 | HIF1A (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3174870-B1 | THIENO [3,2-D]PYRIMIDINES, FURO [3,2,D]PYRIMIDINES AND PYRROLO [3,2-D]PYRIMIDINES USEFUL FOR TREATING RESPIRATORY SYNCITIAL VIRUS INFECTIONS | GILEAD SCIENCES INC (US) | 2020-04-15 | — | — | EP | disclosed |