⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20642796 | 1.00 | — | — | |
| SCHEMBL19644592 | 0.86 | HIF1A (0.30) | — | |
| SCHEMBL21880486 | 0.76 | — | — | |
| SCHEMBL19644580 | 0.74 | HIF1A (0.30) | — | |
| SCHEMBL21880622 | 0.73 | HIF1A (0.30) | — | |
| SCHEMBL20959986 | 0.73 | POLRMT (0.34) | — | |
| SCHEMBL19778892 | 0.73 | POLRMT (0.34) | — | |
| SCHEMBL19644600 | 0.68 | POLRMT (0.36) | — | |
| SCHEMBL19644567 | 0.67 | — | — | |
| SCHEMBL20756525 | 0.67 | POLRMT (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180072755-A1 | THIENO[3,2-d]PYRIMIDINE, FURO[3,2-d]PYRIMIDINE, AND PYRROLO[3,2-D]PYRIMIDINES USEFUL FOR TREATING RESPIRATORY SYNCITIAL VIRUS INFECTIONS | GILEAD SCIENCES, INC. | 2018-03-15 | — | — | US | disclosed |