SCHEMBL21880935

SCHEMBL21880935

CCC1(CC)CC(CCN=O)OC1=O

nearest known ligand 0.48

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 18/20 0.48
TMEM97 Q5BJF2 3/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21880880 0.82 HTR7 (0.52) HTR7TMEM97
SCHEMBL16150771 0.79 HTR7 (0.50) HTR7TMEM97
SCHEMBL20510919 0.79 HTR7 (0.50) HTR7TMEM97
SCHEMBL576526 0.78 HTR7 (0.48) HTR7TMEM97
SCHEMBL23732613 0.77 HTR7 (0.51) HTR7TMEM97
SCHEMBL18236137 0.77 HTR7 (0.51) HTR7TMEM97
SCHEMBL16149406 0.75 HTR7 (0.46) HTR7TMEM97
SCHEMBL17435912 0.75 HTR7 (0.46) HTR7TMEM97
SCHEMBL23732376 0.74 HTR7 (0.49) HTR7TMEM97
SCHEMBL22672953 0.72 HTR7 (0.70) HTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2970223-B1 NOVEL 5-HYDROXYTRYPTAMINE RECEPTOR 7 ACTIVITY MODULATORS AND THEIR METHOD OF USE UNIV TEMPLE (US) 2020-04-15 EP disclosed