Vipivotide Tetraxetan

Vipivotide Tetraxetan

SCHEMBL21881849

O=C(O)CC[C@H](NC(=O)N[C@@H](CCCCNC(=O)C(Cc1ccc2ccccc2c1)NC(=O)C1CCC(CNC(=O)CN2CCN(CC(=O)O)CCN(CC(=O)O)CCN(CC(=O)O)CC2)CC1)C(=O)O)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3634965-B1 RADIOPHARMACEUTICALS, RADIOIMAGING AGENTS, AND USES THEREOF Clarity Pharmaceuticals Ltd (AU) 2023-02-22 — — EP disclosed
US-20220125957-A1 METHODS OF TREATING CANCER SATHEKGE MIKE (ZA) 2022-04-28 — — US disclosed
US-20210323985-A1 SHIELDING AGENTS AND THEIR USE ENDOCYTE INC (US) 2021-10-21 — — US disclosed
US-10975089-B2 Radiopharmaceuticals, radioimaging agents, and uses thereof Clarity Pharmaceuticals Ltd (AU) 2021-04-13 — — US disclosed
US-20200095257-A1 RADIOPHARMACEUTICALS, RADIOIMAGING AGENTS, AND USES THEREOF THE UNIVERSITY OF MELBOURNE (AU) 2020-03-26 — — US disclosed
WO-2020061458-A1 METHODS OF TREATING CANCER ENDOCYTE, INC. (US) 2020-03-26 — — WO disclosed
WO-2020061293-A1 SHIELDING AGENTS AND THEIR USE ENDOCYTE, INC. (US) 2020-03-26 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220125957-A1 METHODS OF TREATING CANCER PAICS, FOLH1, INHA FOLH1 2/4885
US-10975089-B2 Radiopharmaceuticals, radioimaging agents, and uses thereof SLC30A5, SLC40A1, FOLH1 FOLH1 3/4885
US-20210323985-A1 SHIELDING AGENTS AND THEIR USE PSMA6, PSMA2, PSMA1 FOLH1 10/4885
US-20200095257-A1 RADIOPHARMACEUTICALS, RADIOIMAGING AGENTS, AND USES THEREOF SLC30A5, SLC40A1, FOLH1 FOLH1 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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