Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 13/20 | 0.48 |
| ▸ | CSF1R | P07333 | 6/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 6/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | BRAF | P15056 | 8/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21425751 | 0.87 | KDR (0.49) | KDRCSF1RPDGFRAPDGFRBFLT3 | |
| SCHEMBL21426332 | 0.79 | KDR (0.53) | KDRCSF1RPDGFRAPDGFRBFLT3 | |
| SCHEMBL30890876 | 0.79 | KDR (0.53) | KDRCSF1RPDGFRAPDGFRBFLT3 | |
| SCHEMBL21425524 | 0.76 | CSF1R (0.66) | KDRCSF1RPDGFRAPDGFRBFLT3 | |
| SCHEMBL21772037 | 0.76 | KDR (0.51) | KDRCSF1RPDGFRAPDGFRBFLT3 | |
| SCHEMBL16038279 | 0.75 | CSF1R (0.63) | KDRCSF1RPDGFRAPDGFRBFLT3 | |
| SCHEMBL16059079 | 0.74 | KDR (0.47) | KDRBRAF | |
| SCHEMBL16036678 | 0.72 | KDR (0.52) | KDRBRAF | |
| SCHEMBL16060327 | 0.72 | CSF1R (0.49) | KDRCSF1RPDGFRAPDGFRBFLT3 | |
| SCHEMBL21425522 | 0.72 | CSF1R (0.67) | KDRCSF1RPDGFRAPDGFRBFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3632907-A1 | N-(AZAARYL)CYCLOLACTAM-1-CARBOXAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | Abbisko Therapeutics Co., Ltd. (CN) | 2020-04-08 | — | — | EP | disclosed |