Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 13/20 | 0.53 |
| ▸ | BRAF | P15056 | 8/20 | 0.51 |
| ▸ | CSF1R | P07333 | 4/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.48 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.48 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21426332 | 1.00 | KDR (0.53) | KDRBRAFCSF1RPDGFRAPDGFRB | |
| SCHEMBL16036678 | 0.93 | KDR (0.52) | KDRBRAF | |
| SCHEMBL16037120 | 0.86 | CSF1R (0.44) | KDRBRAFCSF1RPDGFRAPDGFRB | |
| SCHEMBL21772037 | 0.85 | KDR (0.51) | KDRBRAFCSF1RPDGFRAPDGFRB | |
| SCHEMBL16038352 | 0.83 | TGFBR1 (0.48) | CSF1RPDGFRAPDGFRB | |
| SCHEMBL16037156 | 0.82 | KDR (0.56) | KDRBRAFABL1GSK3BDYRK1A | |
| SCHEMBL16059181 | 0.82 | CSF1R (0.55) | KDRBRAFCSF1RPDGFRAPDGFRB | |
| SCHEMBL16037333 | 0.82 | CSF1R (0.45) | CSF1RPDGFRAPDGFRB | |
| SCHEMBL21425751 | 0.80 | KDR (0.49) | KDRBRAFCSF1RPDGFRAPDGFRB | |
| SCHEMBL21425524 | 0.80 | CSF1R (0.66) | KDRBRAFCSF1RPDGFRAPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3632907-B1 | N-(AZAARYL)CYCLOLACTAM-1-CARBOXAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | ABBISKO THERAPEUTICS CO LTD (CN) | 2024-02-28 | — | — | EP | disclosed |