Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 17/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 13/20 | 0.41 |
| ▸ | KIT | P10721 | 3/20 | 0.41 |
| ▸ | MET | P08581 | 2/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 6/20 | 0.38 |
| ▸ | RAF1 | P04049 | 2/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21882323 | 0.88 | CSF1R (0.47) | CSF1RPDGFRAKITMETPDGFRB | |
| SCHEMBL21425611 | 0.88 | CSF1R (0.55) | CSF1RPDGFRAKITMETPDGFRB | |
| SCHEMBL21425640 | 0.86 | CSF1R (0.45) | CSF1RPDGFRAKITMETPDGFRB | |
| SCHEMBL27117578 | 0.86 | CSF1R (0.43) | CSF1RPDGFRAKITMETPDGFRB | |
| SCHEMBL21785871 | 0.84 | CSF1R (0.40) | CSF1RPDGFRAKITMETPDGFRB | |
| SCHEMBL27118054 | 0.83 | CSF1R (0.46) | CSF1RPDGFRAKITMETPDGFRB | |
| SCHEMBL21425562 | 0.82 | RAF1 (0.39) | CSF1RPDGFRAMETPDGFRBRAF1 | |
| SCHEMBL21882305 | 0.80 | RAF1 (0.38) | CSF1RPDGFRAMETPDGFRBRAF1 | |
| SCHEMBL21426343 | 0.77 | CSF1R (0.58) | CSF1RPDGFRAKITMETPDGFRB | |
| SCHEMBL21425618 | 0.76 | CSF1R (0.56) | CSF1RPDGFRAKITMETPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3632907-B1 | N-(AZAARYL)CYCLOLACTAM-1-CARBOXAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | ABBISKO THERAPEUTICS CO LTD (CN) | 2024-02-28 | — | — | EP | disclosed |
| EP-3632907-A1 | N-(AZAARYL)CYCLOLACTAM-1-CARBOXAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | Abbisko Therapeutics Co., Ltd. (CN) | 2020-04-08 | — | — | EP | disclosed |