Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 20/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21227089 | 0.85 | CRHR1 (0.60) | CRHR1 | |
| SCHEMBL5599786 | 0.79 | CRHR1 (0.74) | CRHR1 | |
| SCHEMBL5599550 | 0.75 | CRHR1 (1.00) | CRHR1 | |
| SCHEMBL29482251 | 0.73 | CRHR1 (1.00) | CRHR1 | |
| SCHEMBL5600844 | 0.73 | CRHR1 (1.00) | CRHR1 | |
| SCHEMBL5872522 | 0.73 | CRHR1 (1.00) | CRHR1 | |
| SCHEMBL14350188 | 0.73 | CRHR1 (0.61) | CRHR1 | |
| Hydrochloric Acid SCHEMBL29601420 | 0.72 | CRHR1 (0.98) | CRHR1 | |
| Hydrochloric Acid SCHEMBL5872497 | 0.72 | CRHR1 (0.98) | CRHR1 | |
| SCHEMBL14350206 | 0.72 | CRHR1 (0.63) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3623483-A1 | METHOD FOR PREDICTING A TREATMENT RESPONSE TO A CRHR1 ANTAGONIST AND/OR A V1B ANTAGONIST IN A PATIENT WITH DEPRESSIVE AND/OR ANXIETY SYMPTOMS | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2020-03-18 | — | — | EP | disclosed |