SCHEMBL21882571

SCHEMBL21882571

CNc1ccc(Cc2cccc(N)c2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.51
CA2 P00918 1/20 0.51
CA9 Q16790 1/20 0.51
CYP19A1 P11511 2/20 0.48
MAOA P21397 2/20 0.46
MAOB P27338 2/20 0.46
CYP3A4 P08684 3/20 0.44
CYP11B1 P15538 2/20 0.44
CYP11B2 P19099 2/20 0.44
CYP17A1 P05093 1/20 0.44
TDP1 Q9NUW8 2/20 0.41
ALDH1A1 P00352 2/20 0.41
TSHR P16473 2/20 0.41
CASP1 P29466 1/20 0.39
RECQL P46063 1/20 0.39
PARP1 P09874 1/20 0.38
SAE1 Q9UBE0 1/20 0.38
UBA2 Q9UBT2 1/20 0.38
MTNR1A P48039 1/20 0.38
MTNR1B P49286 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29569802 0.86 CA1 (0.62) CA1CA2CA9CYP19A1MAOA
SCHEMBL3482569 0.86 CA1 (0.62) CA1CA2CA9CYP19A1MAOA
SCHEMBL30324526 0.86 CA1 (0.62) CA1CA2CA9CYP19A1MAOA
SCHEMBL9719373 0.86 CA1 (0.62) CA1CA2CA9CYP19A1MAOA
SCHEMBL8732128 0.82 TSHR (0.46) CYP11B1CYP11B2CYP17A1ALDH1A1TSHR
SCHEMBL16443297 0.82 CYP19A1 (0.69) CA1CA2CA9CYP19A1MAOA
4,4'-Methylenedianiline SCHEMBL20917783 0.82 CYP19A1 (0.69) CA1CA2CA9CYP19A1MAOA
SCHEMBL29929353 0.82 CYP19A1 (0.69) CA1CA2CA9CYP19A1MAOA
SCHEMBL125532 0.82 CYP19A1 (0.69) CA1CA2CA9CYP19A1MAOA
SCHEMBL49433 0.82 MAOB (0.62) CA1CA2CA9CYP19A1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2534191-B1 PHOTOALIGNING MATERIAL WITH LATERAL SUBSTITUTION ROLIC TECH AG (CH) 2020-04-15 EP disclosed