Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.45 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 2/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18905641 | 0.91 | TSHR (0.48) | TSHRSAE1UBA2APPMTNR1A | |
| SCHEMBL12707605 | 0.89 | TSHR (0.54) | TSHRAPPMTNR1AMTNR1BLMNA | |
| SCHEMBL22602000 | 0.88 | SAE1 (0.46) | TSHRSAE1UBA2APPHTT | |
| SCHEMBL21882571 | 0.82 | CA1 (0.51) | TSHRSAE1UBA2MTNR1AMTNR1B | |
| SCHEMBL12852535 | 0.82 | CYP17A1 (0.49) | TSHRLMNAHTTSMN1; SMN2HPGD | |
| SCHEMBL1108578 | 0.82 | TSHR (0.62) | TSHRLMNAHTTSMN1; SMN2HPGD | |
| Hydrochloric Acid SCHEMBL28230977 | 0.82 | LTA4H (0.59) | SAE1UBA2APPMTNR1AMTNR1B | |
| SCHEMBL291602 | 0.82 | ALDH1A1 (0.52) | TSHRSAE1UBA2APPLMNA | |
| SCHEMBL24146817 | 0.82 | MAPT (0.48) | SAE1UBA2HTTLTA4HMAPT | |
| SCHEMBL27919316 | 0.79 | TEAD4 (0.48) | TSHRLMNAHTTSMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5725948-A | POLYIMIDE FROM A BISMALEIMIDE AND A DIAMINE | TOMOEGAWA PAPER CO., LTD. (JP) | 1998-03-10 | — | — | US | disclosed |
| US-5696235-A | CONTAINING A BISMALEIMIDE; HEAT RESISTANCE, PROCESSABILITY; SOLUBLE IN VARIOUS ORGANIC SOLVENTS | TOMOEGAWA PAPER CO., LTD. (JP) | 1997-12-09 | — | — | US | disclosed |