SCHEMBL2188271

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14138214	0.86	SMN1; SMN2 (0.52)	SMN1; SMN2HTTRXFP1KDM4EALDH1A1
	SCHEMBL2186229	0.83	MAPT (0.50)	SMN1; SMN2HTTRXFP1KDM4EALDH1A1
	SCHEMBL12697371	0.76	KMT2A (0.66)	SMN1; SMN2HTTKDM4EALDH1A1KMT2A
	SCHEMBL16333844	0.74	PTGER4 (0.50)	SMN1; SMN2HTTKDM4EALDH1A1HPGD
	SCHEMBL16334299	0.74	HDAC1 (0.51)	SMN1; SMN2HTTKDM4EALDH1A1HPGD
	SCHEMBL12444474	0.74	MAPT (0.48)	SMN1; SMN2HTTRXFP1KDM4EALDH1A1
	SCHEMBL12697314	0.74	KMT2A (0.59)	SMN1; SMN2HTTHPGDKMT2ACYP1A2
	SCHEMBL15726043	0.74	KMT2A (0.52)	SMN1; SMN2HTTKDM4EALDH1A1HPGD
	SCHEMBL6722951	0.74	KMT2A (0.63)	SMN1; SMN2HTTKDM4EALDH1A1KMT2A
	SCHEMBL12697363	0.73	KMT2A (0.71)	SMN1; SMN2HTTKDM4EALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.