SCHEMBL2186229

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12444474	0.86	MAPT (0.48)	MAPTTHRBHTTSMN1; SMN2GAA
	SCHEMBL14536680	0.85	MAPT (0.47)	MAPTTHRBLIPGGAARXFP1
	SCHEMBL14138214	0.84	SMN1; SMN2 (0.52)	MAPTTHRBLIPGHTTSMN1; SMN2
	SCHEMBL8981479	0.83	CNR2 (0.55)	MAPTTHRBHTTSMN1; SMN2GAA
	SCHEMBL2188271	0.83	SMN1; SMN2 (0.51)	LIPGHTTSMN1; SMN2GAAPTGER4
	SCHEMBL2186250	0.82	LMNA (0.60)	MAPTTHRBHTTSMN1; SMN2RXFP1
	SCHEMBL92995	0.78	CNR2 (0.52)	MAPTTHRBLIPGGAAPTGER4
	SCHEMBL92997	0.77	CNR2 (0.51)	MAPTTHRBLIPGGAAPTGER4
	SCHEMBL12697369	0.77	KMT2A (0.62)	MAPTTHRBHTTSMN1; SMN2GAA
	SCHEMBL83038	0.76	LMNA (0.58)	MAPTTHRBLIPGHTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.