Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 12/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 6/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21820752 | 0.88 | KEAP1 (0.48) | CHRM3CHRM2CHRM4CHRM1ATM | |
| SCHEMBL29005770 | 0.87 | KEAP1 (0.47) | CHRM3CHRM2CHRM4CHRM1ELANE | |
| SCHEMBL21820701 | 0.86 | CHRM3 (0.40) | CHRM3CHRM2CHRM4CHRM1ELANE | |
| SCHEMBL2655676 | 0.85 | CHRM3 (0.64) | CHRM3CHRM2CHRM4CHRM1KCNN4 | |
| SCHEMBL4208886 | 0.85 | CHRM3 (0.64) | CHRM3CHRM2CHRM4CHRM1KCNN4 | |
| SCHEMBL21820625 | 0.83 | ELANE (0.40) | CHRM3ELANEATMTDP1L3MBTL1 | |
| SCHEMBL4245314 | 0.82 | CHRM3 (0.60) | CHRM3CHRM2CHRM4CHRM1KCNN4 | |
| SCHEMBL7800561 | 0.80 | CHRM3 (0.47) | CHRM3CHRM2CHRM4CHRM1GAA | |
| SCHEMBL4238807 | 0.80 | CHRM3 (0.47) | CHRM3CHRM2CHRM4CHRM1TDP1 | |
| SCHEMBL4238414 | 0.80 | CHRM3 (0.47) | CHRM3CHRM2CHRM4CHRM1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10961266-B2 | Chemoselective methylene hydroxylation in aromatic molecules | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2021-03-30 | — | — | US | disclosed |
| US-20200087331-A1 | CHEMOSELECTIVE METHYLENE HYDROXYLATION IN AROMATIC MOLECULES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2020-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10961266-B2 | Chemoselective methylene hydroxylation in aromatic molecules | PAH, DBH, AHR | CHRM3 1224/4885CHRM2 2909/4885CHRM4 1506/4885 |
| US-20200087331-A1 | CHEMOSELECTIVE METHYLENE HYDROXYLATION IN AROMATIC MOLECULES | PAH, DBH, AHR | CHRM3 1224/4885CHRM2 2909/4885CHRM4 1506/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.