Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4296465 | 0.87 | HPGD (0.57) | ALDH1A1SMN1; SMN2HPGDFKBP1AMAPT | |
| SCHEMBL6639156 | 0.87 | ACE (0.59) | ALDH1A1HPGDACEFKBP1AALOX5 | |
| SCHEMBL10509005 | 0.87 | ACE (0.59) | ALDH1A1HPGDACEFKBP1AALOX5 | |
| SCHEMBL11494753 | 0.85 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2HTTNPC1ACE | |
| SCHEMBL5740221 | 0.84 | SMN1; SMN2 (0.54) | ALDH1A1SMN1; SMN2HTTHPGDNPC1 | |
| SCHEMBL5740226 | 0.84 | SMN1; SMN2 (0.54) | ALDH1A1SMN1; SMN2HTTHPGDNPC1 | |
| SCHEMBL11162409 | 0.81 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2HTTHPGDACE | |
| SCHEMBL30600066 | 0.81 | DPP4 (0.45) | ALDH1A1SMN1; SMN2HTTHPGDACE | |
| SCHEMBL22811118 | 0.81 | ALDH1A1 (0.55) | ALDH1A1ACE | |
| SCHEMBL28514213 | 0.80 | ALDH1A1 (0.55) | ALDH1A1HPGDNPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10961266-B2 | Chemoselective methylene hydroxylation in aromatic molecules | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2021-03-30 | — | — | US | disclosed |
| US-20200087331-A1 | CHEMOSELECTIVE METHYLENE HYDROXYLATION IN AROMATIC MOLECULES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2020-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10961266-B2 | Chemoselective methylene hydroxylation in aromatic molecules | PAH, DBH, AHR | ALDH1A1 415/4885SMN1; SMN2 2130/4885HTT 1492/4885 |
| US-20200087331-A1 | CHEMOSELECTIVE METHYLENE HYDROXYLATION IN AROMATIC MOLECULES | PAH, DBH, AHR | ALDH1A1 415/4885SMN1; SMN2 2130/4885HTT 1492/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.