Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 14/20 | 0.68 |
| ▸ | NPY4R | P50391 | 6/20 | 0.53 |
| ▸ | NPY1R | P25929 | 5/20 | 0.53 |
| ▸ | NPY2R | P49146 | 4/20 | 0.53 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21286534 | 0.90 | OPRK1 (0.61) | OPRK1 | |
| SCHEMBL21286491 | 0.90 | OPRK1 (0.72) | OPRK1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL10316475 | 0.90 | OPRK1 (0.85) | OPRK1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL13290867 | 0.90 | OPRK1 (0.78) | OPRK1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL13290871 | 0.89 | OPRK1 (0.65) | OPRK1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL18413282 | 0.89 | OPRK1 (0.83) | OPRK1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL13290888 | 0.88 | OPRK1 (0.65) | OPRK1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL10316469 | 0.88 | OPRK1 (0.65) | OPRK1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL24001130 | 0.87 | OPRK1 (0.65) | OPRK1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL21286624 | 0.87 | OPRK1 (0.81) | OPRK1NPY4RNPY1RNPY2RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020056249-A1 | ORAL FORMULATIONS OF KAPPA OPIOID RECEPTOR AGONISTS | CARA THERAPEUTICS, INC. (US) | 2020-03-19 | — | — | WO | disclosed |