Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 13/20 | 0.59 |
| ▸ | REN | P00797 | 6/20 | 0.51 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21886333 | 0.90 | OPRK1 (0.72) | OPRK1REN | |
| SCHEMBL11927500 | 0.90 | OPRK1 (0.72) | OPRK1REN | |
| SCHEMBL24001142 | 0.88 | OPRK1 (0.65) | OPRK1CTSS | |
| SCHEMBL20363365 | 0.88 | OPRK1 (0.75) | OPRK1REN | |
| SCHEMBL11927499 | 0.84 | OPRK1 (0.70) | OPRK1REN | |
| SCHEMBL26648563 | 0.83 | OPRK1 (0.61) | OPRK1REN | |
| SCHEMBL11927488 | 0.83 | OPRK1 (0.69) | OPRK1 | |
| SCHEMBL24360600 | 0.82 | OPRK1 (0.63) | OPRK1CTSS | |
| SCHEMBL18413122 | 0.82 | OPRK1 (0.74) | OPRK1REN | |
| SCHEMBL20363358 | 0.82 | OPRK1 (0.73) | OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020056249-A1 | ORAL FORMULATIONS OF KAPPA OPIOID RECEPTOR AGONISTS | CARA THERAPEUTICS, INC. (US) | 2020-03-19 | — | — | WO | disclosed |