Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 3/20 | 0.42 |
| ▸ | FAP | Q12884 | 5/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAP1LC3B | Q9GZQ8 | 2/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.33 |
| ▸ | CHRNG | P07510 | 1/20 | 0.33 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.33 |
| ▸ | CHRND | Q07001 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NPY1R | P25929 | 1/20 | 0.32 |
| ▸ | NPY2R | P49146 | 1/20 | 0.32 |
| ▸ | NPY4R | P50391 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24916473 | 1.00 | FURIN (0.42) | FURINFAPHTTMAP1LC3BSIRT2 | |
| SCHEMBL22432743 | 0.94 | FAP (0.40) | FURINFAPHTTMAP1LC3BSIRT2 | |
| SCHEMBL23943282 | 0.94 | FAP (0.40) | FURINFAPHTTMAP1LC3BSIRT2 | |
| SCHEMBL22138625 | 0.94 | FAP (0.40) | FURINFAPHTTMAP1LC3BSIRT2 | |
| SCHEMBL24224636 | 0.94 | FAP (0.40) | FURINFAPHTTMAP1LC3BSIRT2 | |
| SCHEMBL16946352 | 0.94 | FAP (0.40) | FURINFAPHTTMAP1LC3BSIRT2 | |
| SCHEMBL25450085 | 0.94 | FAP (0.40) | FURINFAPHTTMAP1LC3BSIRT2 | |
| SCHEMBL27197502 | 0.94 | FAP (0.40) | FURINFAPHTTMAP1LC3BSIRT2 | |
| SCHEMBL31045324 | 0.93 | FAP (0.40) | FURINFAPHTTMAP1LC3BSIRT2 | |
| SCHEMBL31045407 | 0.93 | FAP (0.40) | FURINFAPHTTMAP1LC3BSIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020058290-A1 | DRUG CONJUGATE COMPRISING QUINOLINE DERIVATIVES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2020-03-26 | — | — | WO | disclosed |