Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | GAA | P10253 | 3/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | PKM | P14618 | 2/20 | 0.79 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.79 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.79 |
| ▸ | LMNA | P02545 | 1/20 | 0.74 |
| ▸ | MAPT | P10636 | 1/20 | 0.74 |
| ▸ | TSHR | P16473 | 2/20 | 0.72 |
| ▸ | RECQL | P46063 | 1/20 | 0.70 |
| ▸ | USP2 | O75604 | 1/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.69 |
| ▸ | NPC1 | O15118 | 1/20 | 0.68 |
| ▸ | RAB9A | P51151 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21800654 | 0.91 | KMT2A (0.84) | KMT2AGAAMEN1PKMAPOBEC3A | |
| SCHEMBL21800626 | 0.91 | KMT2A (0.82) | KMT2AGAAMEN1PKMAPOBEC3A | |
| SCHEMBL21800637 | 0.89 | KMT2A (0.79) | KMT2AGAAMEN1PKMAPOBEC3A | |
| SCHEMBL20258829 | 0.88 | KMT2A (0.83) | KMT2AGAAMEN1PKMAPOBEC3A | |
| SCHEMBL21766071 | 0.88 | GAA (0.79) | KMT2AGAAMEN1PKMAPOBEC3A | |
| SCHEMBL21800716 | 0.87 | KMT2A (0.76) | KMT2AGAAMEN1PKMAPOBEC3A | |
| SCHEMBL20511829 | 0.87 | KMT2A (0.77) | KMT2AGAAMEN1PKMAPOBEC3A | |
| SCHEMBL21800666 | 0.86 | KMT2A (0.74) | KMT2AGAAMEN1PKMAPOBEC3A | |
| SCHEMBL21800694 | 0.84 | KMT2A (0.76) | KMT2AGAAMEN1PKMAPOBEC3A | |
| SCHEMBL20258762 | 0.84 | KMT2A (0.76) | KMT2AGAAMEN1PKMAPOBEC3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200087258-A1 | INHIBITOR OF CITRATE TRANSPORTER AND THEIR USE IN THERAPY | ETERNYGEN GMBH (DE) | 2020-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200087258-A1 | INHIBITOR OF CITRATE TRANSPORTER AND THEIR USE IN THERAPY | CS, SLC2A1, SLC2A2 | KMT2A 1382/4885GAA 108/4885MEN1 3535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.