Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | AHR | P35869 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.35 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL946635 | 0.81 | SMN1; SMN2 (0.67) | L3MBTL1SMN1; SMN2AHRCHRM2ALDH1A1 | |
| SCHEMBL29965849 | 0.81 | SMN1; SMN2 (0.67) | L3MBTL1SMN1; SMN2AHRCHRM2ALDH1A1 | |
| SCHEMBL24608558 | 0.80 | SMN1; SMN2 (0.54) | L3MBTL1SMN1; SMN2AHRCHRM2ALDH1A1 | |
| SCHEMBL29750392 | 0.80 | SMN1; SMN2 (0.54) | L3MBTL1SMN1; SMN2AHRCHRM2ALDH1A1 | |
| SCHEMBL13330624 | 0.79 | CHRM2 (0.49) | L3MBTL1SMN1; SMN2CHRM2ALDH1A1CHRM3 | |
| SCHEMBL23029720 | 0.79 | SMN1; SMN2 (0.44) | L3MBTL1SMN1; SMN2AHRCHRM2ALDH1A1 | |
| SCHEMBL24977021 | 0.78 | SMN1; SMN2 (0.42) | L3MBTL1SMN1; SMN2AHRCHRM2ALDH1A1 | |
| SCHEMBL4728011 | 0.78 | SMN1; SMN2 (0.50) | L3MBTL1SMN1; SMN2AHRCHRM2ALDH1A1 | |
| SCHEMBL6921056 | 0.77 | SMN1; SMN2 (0.67) | L3MBTL1SMN1; SMN2AHRCHRM2ALDH1A1 | |
| SCHEMBL12717303 | 0.77 | SMN1; SMN2 (0.67) | L3MBTL1SMN1; SMN2AHRCHRM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2736885-B1 | QUINOLINE-, QUINOXALINE OR BENZOTHIAZOLE BASED CYSTEINYL LEUKOTRIENE ANTAGONISTS (LTC4) | SUN PHARMA ADVANCED RES CO LTD (IN) | 2020-03-25 | — | — | EP | disclosed |