Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | NMBR | P28336 | 1/20 | 0.35 |
| ▸ | GRPR | P30550 | 1/20 | 0.35 |
| ▸ | BRS3 | P32247 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4728011 | 0.84 | SMN1; SMN2 (0.50) | SMN1; SMN2L3MBTL1CHRM2AHRKCNH2 | |
| SCHEMBL23029668 | 0.82 | SMN1; SMN2 (0.41) | SMN1; SMN2L3MBTL1CHRM2KCNH2ALDH1A1 | |
| SCHEMBL21883522 | 0.79 | L3MBTL1 (0.55) | SMN1; SMN2L3MBTL1CHRM2AHRALDH1A1 | |
| SCHEMBL13330624 | 0.78 | CHRM2 (0.49) | SMN1; SMN2L3MBTL1CHRM2KCNH2ALDH1A1 | |
| SCHEMBL18427298 | 0.77 | SMN1; SMN2 (0.47) | SMN1; SMN2L3MBTL1CHRM2KCNH2ALDH1A1 | |
| SCHEMBL24737687 | 0.76 | CYP19A1 (0.37) | BRS3CYP2D6 | |
| SCHEMBL24977021 | 0.76 | SMN1; SMN2 (0.42) | SMN1; SMN2L3MBTL1CHRM2AHRKCNH2 | |
| SCHEMBL19307846 | 0.76 | — | — | |
| SCHEMBL13100469 | 0.76 | SMN1; SMN2 (0.50) | SMN1; SMN2L3MBTL1CHRM2AHRKCNH2 | |
| SCHEMBL1478334 | 0.75 | SMN1; SMN2 (0.48) | SMN1; SMN2L3MBTL1CHRM2AHRKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230150921-A1 | PHENOLIC ACID LIPID BASED CATIONIC LIPIDS | TRANSLATE BIO, INC. (US) | 2023-05-18 | — | — | US | disclosed |
| WO-2023278754-A1 | COMPOSITIONS FOR DELIVERY OF MRNA | TRANSLATE BIO, INC. (US) | 2023-01-05 | — | — | WO | disclosed |
| WO-2021035101-A1 | MOLECULES THAT BIND TO TDP-43 FOR THE TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS AND RELATED DISORDERS | BIOHAVEN THERAPEUTICS LTD. (US) | 2021-02-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230150921-A1 | PHENOLIC ACID LIPID BASED CATIONIC LIPIDS | SLC27A1, SREBF1, SREBF2 | SMN1; SMN2 2738/4885L3MBTL1 1302/4885CHRM2 4819/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.