Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | SELPLG | Q14242 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 3/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12247340 | 0.85 | KDM4E (0.53) | CYP1A2SELPLGKDM4ETSHRALOX15 | |
| SCHEMBL13892962 | 0.83 | CYP1A2 (0.39) | CYP1A2CNR2P2RX7SELPLGHDAC4 | |
| SCHEMBL3935150 | 0.82 | PIM1 (0.43) | PIM1CYP1A2CNR2P2RX7PARP1 | |
| SCHEMBL9298348 | 0.81 | PIM1 (0.42) | PIM1CNR2P2RX7PARP1KDM4E | |
| SCHEMBL29049786 | 0.81 | PIM1 (0.42) | PIM1CYP1A2CNR2P2RX7PARP1 | |
| SCHEMBL18672435 | 0.81 | CYP1A2 (0.47) | CYP1A2ALDH1A1 | |
| SCHEMBL22096789 | 0.80 | PIM1 (0.36) | PIM1CYP1A2CNR2P2RX7PARP1 | |
| SCHEMBL23491120 | 0.79 | PIM1 (0.45) | PIM1CYP1A2CNR2P2RX7PARP1 | |
| SCHEMBL3631871 | 0.78 | TSHR (0.41) | HDAC4HDAC2HDAC8TSHRALOX15 | |
| SCHEMBL22234567 | 0.75 | PIM1 (0.43) | PIM1CNR2KDM4ETSHRALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10597377-B2 | Somatostatin modulators and uses thereof | Crinetics Pharmaceuticals, Inc. (US) | 2020-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10597377-B2 | Somatostatin modulators and uses thereof | SSTR5, SSTR2, SSTR4 | PIM1 3355/4885CYP1A2 4769/4885CNR2 443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.