SCHEMBL29049786

SCHEMBL29049786

CC(N)c1cccc(C(N)=O)n1

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 1/20 0.42
PARP1 P09874 1/20 0.42
IRAK4 Q9NWZ3 2/20 0.40
KDM4E B2RXH2 1/20 0.38
ALOX15 P16050 1/20 0.38
TSHR P16473 1/20 0.38
ACMSD Q8TDX5 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
CNR2 P34972 2/20 0.37
P2RX7 Q99572 1/20 0.36
XIAP P98170 1/20 0.36
BIRC2 Q13490 1/20 0.36
ADA P00813 2/20 0.35
LMNA P02545 1/20 0.34
NNMT P40261 1/20 0.34
CYP1A2 P05177 1/20 0.34
ALDH1A1 P00352 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3935150 0.87 PIM1 (0.43) PIM1PARP1KDM4EALOX15TSHR
SCHEMBL9298348 0.85 PIM1 (0.42) PIM1PARP1IRAK4KDM4EALOX15
SCHEMBL23491120 0.84 PIM1 (0.45) PIM1PARP1KDM4EALOX15TSHR
SCHEMBL21883573 0.81 PIM1 (0.39) PIM1PARP1KDM4EALOX15TSHR
SCHEMBL29049789 0.81 P2RX7 (0.60) IRAK4CNR2P2RX7CYP1A2ALDH1A1
SCHEMBL22234567 0.79 PIM1 (0.43) PIM1IRAK4KDM4EALOX15TSHR
SCHEMBL29444559 0.79 PIM1 (0.43) PIM1IRAK4KDM4EALOX15TSHR
Hydrochloric Acid SCHEMBL31211911 0.78 PIM1 (0.42) PIM1IRAK4KDM4EALOX15TSHR
SCHEMBL522063 0.77 CYP1A2 (0.38) IRAK4LMNACYP1A2ALDH1A1
Pyridine Dicarboxamide SCHEMBL29587789 0.77 TSHR (0.59) PIM1PARP1KDM4EALOX15TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116410441-A Water-based polyurethane-acrylate emulsion and preparation method thereof 万华化学集团股份有限公司 2023-07-11 CN disclosed