Itaconate

Itaconate

SCHEMBL218838

C=C(CC(=O)O)C(=O)O.C=C(Cl)Cl.C=CC(=O)OC

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.60
ALOX15 P16050 1/20 0.60
TSHR P16473 6/20 0.32
HCAR2 Q8TDS4 2/20 0.32
KEAP1 Q14145 1/20 0.32
NFE2L2 Q16236 1/20 0.32
HPGD P15428 1/20 0.32
ALDH1A1 P00352 3/20 0.31
TP53 P04637 2/20 0.31
HIF1A Q16665 2/20 0.31
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Itaconate SCHEMBL6367963 0.94 HSD17B10 (0.67) HSD17B10ALOX15TSHRHCAR2KEAP1
Itaconate SCHEMBL27781638 0.94 HSD17B10 (0.67) HSD17B10ALOX15TSHRHCAR2KEAP1
Itaconate SCHEMBL11231577 0.93 HSD17B10 (0.64) HSD17B10ALOX15TSHRHCAR2KEAP1
Itaconate SCHEMBL11231578 0.93 HSD17B10 (0.64) HSD17B10ALOX15TSHRHCAR2KEAP1
Itaconate SCHEMBL18396077 0.91 HSD17B10 (0.74) HSD17B10ALOX15TSHRHCAR2KEAP1
Itaconate SCHEMBL28904531 0.86 ALOX15 (0.67) HSD17B10ALOX15TSHRHCAR2KEAP1
Itaconate SCHEMBL6226414 0.85 HSD17B10 (0.55) HSD17B10ALOX15TSHRHCAR2HPGD
Itaconate SCHEMBL2542647 0.85 ALOX15 (0.55) HSD17B10ALOX15TSHR
Itaconate SCHEMBL9056840 0.85 ALOX15 (0.55) HSD17B10ALOX15TSHR
Itaconate SCHEMBL28357869 0.85 ALOX15 (0.55) HSD17B10ALOX15TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 675 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0645673-B1 Photographic element provided with a backing layer and method for manufacture thereof EASTMAN KODAK CO (US) 2000-11-22 EP claimed
EP-0645673-A2 Photographic element provided with a backing layer and method for manufacture thereof EASTMAN KODAK COMPANY (US) 1995-03-29 EP claimed
US-5376518-A Photographic element provided with a backing layer and method for manufacture thereof EASTMAN KODAK COMPANY (US) 1994-12-27 US claimed
US-5358834-A Imaging master in graphic arts; having a blocked gelatin-hardening agent, filter dye, antihalant EASTMAN KODAK COMPANY (US) 1994-10-25 US claimed
US-4645731-A SLIGHTLY THICKER SUPPORT FILM COATED ON BOTH SIDES WITH A SARAN-TYPE MOISTURE BARRIER COATING; DIMENSIONAL STABILITY E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-02-24 US claimed
US-3932179-A Electrophotographic element containing a polymeric multi-phase interlayer EASTMAN KODAK COMPANY (US) 1976-01-13 US claimed
JP-8050344-A None JP disclosed
JP-56097346-A None JP disclosed
US-20230406021-A1 INKJET-PRINTED ARTICLES BANK OF AMERICA, N.A., AS AGENT 2023-12-21 US disclosed
US-11813882-B2 Inkjet printed articles and method of making EASTMAN KODAK COMPANY (US) 2023-11-14 US disclosed
CN-116348307-A Aqueous composition and opaque coating provided thereby 伊斯曼柯达公司 2023-06-27 CN disclosed
WO-2023057419-A1 CONDUCTIVE INKS AGFA-GEVAERT NV (BE) 2023-04-13 WO disclosed
EP-4163343-A1 CONDUCTIVE INKS AGFA-GEVAERT NV (BE) 2023-04-12 EP disclosed
US-4199362-A WITH POLYMER LATEX TIMING LAYER FUJI PHOTO FILM CO., LTD. (JP) 1980-04-22 US disclosed
US-4196001-A ANIONIC POLYMERIC POLYELECTROLYTE, POLYVINYL ALCOHOL BINDER, ACID ACTING CROSSLINKING AGENT EASTMAN KODAK COMPANY (US) 1980-04-01 US disclosed
US-4157918-A PROOF SHEET CONTAINING DIAZO MATERIAL AND COPOLYESTER ADHESION PROMOTER AMERICAN HOECHST CORPORATION (US) 1979-06-12 US disclosed
US-4115126-A Magenta triphenylmethane antihalation dyes for photographic elements E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-09-19 US disclosed
US-4062681-A Electrophotographic element having a hydrophobic, cured, highly cross-linked polymeric overcoat layer EASTMAN KODAK COMPANY (US) 1977-12-13 US disclosed
US-4002802-A COATING A THERMOPLASTIC RESIN FILM WITH AN AQUEOUS POLYMERIC EMULSION E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-01-11 US disclosed
US-3932179-A Electrophotographic element containing a polymeric multi-phase interlayer EASTMAN KODAK COMPANY (US) 1976-01-13 US disclosed