Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 6/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.39 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.39 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.34 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 2/20 | 0.34 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19142866 | 0.79 | TAS1R3 (0.35) | TP53GRIK1GRIK2MEN1KMT2A | |
| SCHEMBL28923090 | 0.77 | HCAR2 (0.43) | HCAR2TSHRTP53EGLN1EGLN3 | |
| SCHEMBL8919853 | 0.76 | TSHR (0.45) | HCAR2TSHRTP53EGLN1EGLN3 | |
| SCHEMBL8919843 | 0.76 | TSHR (0.45) | HCAR2TSHRTP53EGLN1EGLN3 | |
| SCHEMBL17461678 | 0.75 | — | — | |
| SCHEMBL20365820 | 0.75 | — | — | |
| SCHEMBL18407607 | 0.75 | — | — | |
| SCHEMBL30695271 | 0.74 | HCAR2 (0.41) | HCAR2TSHRTP53EGLN1EGLN3 | |
| SCHEMBL13347104 | 0.74 | HCAR2 (0.41) | HCAR2TSHRTP53EGLN1EGLN3 | |
| SCHEMBL30695273 | 0.74 | HCAR2 (0.41) | HCAR2TSHRTP53EGLN1EGLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3255044-B1 | DIAZA-BENZOFLUORANTHRENE COMPOUNDS | HARBIN PHARMACEUTICAL GROUP CO LTD GENERAL PHARMACEUTICAL FACTORY (CN) | 2020-04-01 | — | — | EP | disclosed |