Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27006946 | 0.83 | VNN1 (0.37) | VNN1HSD11B1CHRM2CHRM4CHRM5 | |
| SCHEMBL27384279 | 0.83 | ATM (0.38) | VNN1HSD11B1CHRM2CHRM4CHRM5 | |
| SCHEMBL29620027 | 0.83 | VNN1 (0.37) | VNN1HSD11B1CHRM2CHRM4CHRM5 | |
| SCHEMBL13207005 | 0.83 | ATM (0.38) | VNN1HSD11B1CHRM2CHRM4CHRM5 | |
| SCHEMBL4335026 | 0.83 | VNN1 (0.37) | VNN1HSD11B1CHRM2CHRM4CHRM5 | |
| SCHEMBL23404413 | 0.83 | VNN1 (0.37) | VNN1HSD11B1CHRM2CHRM4CHRM5 | |
| SCHEMBL19779512 | 0.83 | ATM (0.38) | VNN1HSD11B1CHRM2CHRM4CHRM5 | |
| SCHEMBL14590368 | 0.83 | ATM (0.38) | VNN1HSD11B1CHRM2CHRM4CHRM5 | |
| SCHEMBL610766 | 0.83 | VNN1 (0.37) | VNN1HSD11B1CHRM2CHRM4CHRM5 | |
| SCHEMBL23323367 | 0.78 | JAK3 (0.38) | VNN1HSD11B1CHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112996784-B | Indole derivatives and their use in medicine | 北京越之康泰生物医药科技有限公司 | 2023-05-30 | — | — | CN | disclosed |
| WO-2020057403-A1 | INDOLE DERIVATIVE AND MEDICAL APPLICATION THEREOF | 北京越之康泰生物医药科技有限公司 | 2020-03-26 | — | — | WO | disclosed |