Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 2/20 | 0.57 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.57 |
| ▸ | KDR | P35968 | 6/20 | 0.51 |
| ▸ | AURKA | O14965 | 3/20 | 0.49 |
| ▸ | LCK | P06239 | 3/20 | 0.49 |
| ▸ | TEK | Q02763 | 3/20 | 0.49 |
| ▸ | MET | P08581 | 2/20 | 0.49 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.49 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | LYN | P07948 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2062492 | 0.86 | KDR (0.71) | PDGFRBPDGFRAKDRAURKALCK | |
| SCHEMBL29902462 | 0.86 | KDR (0.71) | PDGFRBPDGFRAKDRAURKALCK | |
| SCHEMBL28567574 | 0.85 | PDGFRA (0.53) | PDGFRBPDGFRAKDRAURKALCK | |
| SCHEMBL2062996 | 0.85 | KDR (0.56) | PDGFRBPDGFRAKDRAURKALCK | |
| Hydrochloric Acid SCHEMBL28914336 | 0.85 | KDR (0.70) | PDGFRBPDGFRAKDRAURKALCK | |
| SCHEMBL29902480 | 0.85 | KDR (0.56) | PDGFRBPDGFRAKDRAURKALCK | |
| SCHEMBL21884846 | 0.85 | KDM4E (0.46) | PDGFRBPDGFRAKDRAURKALCK | |
| SCHEMBL2063822 | 0.83 | KDR (0.53) | PDGFRBPDGFRAKDRAURKALCK | |
| SCHEMBL29902477 | 0.82 | AXL (0.59) | PDGFRBPDGFRAKDRAURKALCK | |
| SCHEMBL3906497 | 0.82 | KDM4E (0.61) | PDGFRBPDGFRAKDRAURKALCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020057403-A1 | INDOLE DERIVATIVE AND MEDICAL APPLICATION THEREOF | 北京越之康泰生物医药科技有限公司 | 2020-03-26 | — | — | WO | disclosed |