Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | AXL | P30530 | 1/20 | 0.44 |
| ▸ | MET | P08581 | 7/20 | 0.43 |
| ▸ | KDR | P35968 | 6/20 | 0.43 |
| ▸ | AURKA | O14965 | 5/20 | 0.43 |
| ▸ | TEK | Q02763 | 5/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 2/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21884829 | 0.85 | PDGFRB (0.57) | METKDRAURKATEKAURKB | |
| SCHEMBL21884831 | 0.81 | KDR (0.56) | KDM4EMEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL8292832 | 0.80 | AXL (0.66) | KDM4EMEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL29902477 | 0.79 | AXL (0.59) | KDM4EALDH1A1AXLMETKDR | |
| SCHEMBL28567574 | 0.78 | PDGFRA (0.53) | AXLMETKDRAURKATEK | |
| SCHEMBL2062492 | 0.73 | KDR (0.71) | METKDRAURKATEKAURKB | |
| SCHEMBL29902462 | 0.73 | KDR (0.71) | METKDRAURKATEKAURKB | |
| SCHEMBL2062996 | 0.72 | KDR (0.56) | METKDRAURKATEKAURKB | |
| Hydrochloric Acid SCHEMBL28914336 | 0.72 | KDR (0.70) | METKDRAURKATEKAURKB | |
| SCHEMBL29902480 | 0.72 | KDR (0.56) | METKDRAURKATEKAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020057403-A1 | INDOLE DERIVATIVE AND MEDICAL APPLICATION THEREOF | 北京越之康泰生物医药科技有限公司 | 2020-03-26 | — | — | WO | disclosed |