Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 8/20 | 0.52 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.52 |
| ▸ | FLT3 | P36888 | 6/20 | 0.40 |
| ▸ | MET | P08581 | 4/20 | 0.40 |
| ▸ | RET | P07949 | 3/20 | 0.40 |
| ▸ | AXL | P30530 | 3/20 | 0.40 |
| ▸ | PLK4 | O00444 | 2/20 | 0.40 |
| ▸ | EPHB6 | O15197 | 2/20 | 0.40 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.40 |
| ▸ | STK10 | O94804 | 2/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.40 |
| ▸ | ABL1 | P00519 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.40 |
| ▸ | LCK | P06239 | 2/20 | 0.40 |
| ▸ | FYN | P06241 | 2/20 | 0.40 |
| ▸ | CSF1R | P07333 | 2/20 | 0.40 |
| ▸ | YES1 | P07947 | 2/20 | 0.40 |
| ▸ | LYN | P07948 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21886115 | 1.00 | KDR (0.52) | KDRPDGFRBFLT3METRET | |
| SCHEMBL21884866 | 1.00 | KDR (0.52) | KDRPDGFRBFLT3METRET | |
| SCHEMBL21884877 | 0.93 | KDR (0.57) | KDRPDGFRBFLT3METRET | |
| SCHEMBL30365130 | 0.93 | KDR (0.57) | KDRPDGFRBFLT3METRET | |
| SCHEMBL21884833 | 0.88 | KDR (0.56) | KDRPDGFRBFLT3METRET | |
| SCHEMBL21884857 | 0.88 | KDR (0.52) | KDRPDGFRBFLT3METRET | |
| SCHEMBL21884855 | 0.88 | KDR (0.52) | KDRPDGFRBFLT3METRET | |
| SCHEMBL21885571 | 0.88 | KDR (0.52) | KDRPDGFRBFLT3METRET | |
| SCHEMBL21884834 | 0.88 | KDR (0.52) | KDRPDGFRBFLT3METRET | |
| SCHEMBL21885573 | 0.88 | KDR (0.52) | KDRPDGFRBFLT3METRET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020057403-A1 | INDOLE DERIVATIVE AND MEDICAL APPLICATION THEREOF | 北京越之康泰生物医药科技有限公司 | 2020-03-26 | — | — | WO | disclosed |