Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 7/20 | 0.56 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | FLT3 | P36888 | 6/20 | 0.43 |
| ▸ | EGFR | P00533 | 3/20 | 0.43 |
| ▸ | RET | P07949 | 3/20 | 0.43 |
| ▸ | AXL | P30530 | 3/20 | 0.43 |
| ▸ | MET | P08581 | 3/20 | 0.43 |
| ▸ | PLK4 | O00444 | 2/20 | 0.43 |
| ▸ | EPHB6 | O15197 | 2/20 | 0.43 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.43 |
| ▸ | STK10 | O94804 | 2/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.43 |
| ▸ | ABL1 | P00519 | 2/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.43 |
| ▸ | LCK | P06239 | 2/20 | 0.43 |
| ▸ | FYN | P06241 | 2/20 | 0.43 |
| ▸ | CSF1R | P07333 | 2/20 | 0.43 |
| ▸ | YES1 | P07947 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21884865 | 0.91 | KDR (0.57) | KDRPDGFRBFLT3EGFRRET | |
| SCHEMBL21885580 | 0.91 | HSD17B10 (0.45) | KDRPDGFRBHSD17B10FLT3EGFR | |
| SCHEMBL21886108 | 0.91 | KDR (0.56) | KDRPDGFRBFLT3EGFRRET | |
| SCHEMBL21886116 | 0.90 | KDR (0.52) | KDRPDGFRBHSD17B10FLT3EGFR | |
| SCHEMBL21884880 | 0.90 | KDR (0.52) | KDRPDGFRBHSD17B10FLT3EGFR | |
| SCHEMBL21885576 | 0.90 | KDR (0.52) | KDRPDGFRBHSD17B10FLT3EGFR | |
| SCHEMBL30365234 | 0.90 | KDR (0.52) | KDRPDGFRBHSD17B10FLT3EGFR | |
| SCHEMBL21886115 | 0.88 | KDR (0.52) | KDRPDGFRBFLT3EGFRRET | |
| SCHEMBL21884869 | 0.88 | KDR (0.52) | KDRPDGFRBFLT3EGFRRET | |
| SCHEMBL21884866 | 0.88 | KDR (0.52) | KDRPDGFRBFLT3EGFRRET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020057403-A1 | INDOLE DERIVATIVE AND MEDICAL APPLICATION THEREOF | 北京越之康泰生物医药科技有限公司 | 2020-03-26 | — | — | WO | disclosed |