Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.78 |
| ▸ | TP53 | P04637 | 7/20 | 0.78 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.78 |
| ▸ | HPGD | P15428 | 5/20 | 0.78 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.78 |
| ▸ | NPC1 | O15118 | 3/20 | 0.78 |
| ▸ | RAB9A | P51151 | 3/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.78 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.78 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.78 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.78 |
| ▸ | RELA | Q04206 | 2/20 | 0.78 |
| ▸ | LMNA | P02545 | 2/20 | 0.78 |
| ▸ | THRB | P10828 | 2/20 | 0.78 |
| ▸ | MEN1 | O00255 | 4/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21417969 | 0.95 | MAPT (0.78) | MAPTTP53CYP3A4ALDH1A1KDM4E | |
| SCHEMBL25330135 | 0.93 | MAPT (0.66) | MAPTTP53CYP3A4ALDH1A1KDM4E | |
| SCHEMBL28635129 | 0.88 | ABCB1 (0.71) | MAPTTP53CYP3A4ALDH1A1KDM4E | |
| SCHEMBL9607679 | 0.88 | MAPT (0.70) | MAPTTP53CYP3A4ALDH1A1KDM4E | |
| 6,4'-Dimethoxyflavone SCHEMBL4281291 | 0.88 | MAPT (1.00) | MAPTTP53CYP3A4ALDH1A1KDM4E | |
| 6,4'-Dimethoxyflavone SCHEMBL29478471 | 0.88 | MAPT (1.00) | MAPTTP53CYP3A4ALDH1A1KDM4E | |
| SCHEMBL9607680 | 0.86 | MAPT (0.72) | MAPTTP53CYP3A4ALDH1A1KDM4E | |
| SCHEMBL20343022 | 0.86 | MAPT (0.80) | MAPTTP53CYP3A4ALDH1A1KDM4E | |
| SCHEMBL18517352 | 0.86 | MAPT (0.72) | MAPTTP53CYP3A4ALDH1A1KDM4E | |
| SCHEMBL20664312 | 0.85 | MAPT (0.56) | MAPTTP53CYP3A4ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3428246-B1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2020-04-15 | — | — | EP | disclosed |