SCHEMBL28635129

SCHEMBL28635129

CC(=O)Oc1ccc2oc(-c3ccccc3)cc(=O)c2c1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 1/20 0.71
ABCG2 Q9UNQ0 1/20 0.71
MAPT P10636 7/20 0.65
KDM4E B2RXH2 5/20 0.65
NPC1 O15118 4/20 0.65
ALDH1A1 P00352 4/20 0.65
RAB9A P51151 3/20 0.65
STS P08842 1/20 0.62
PLA2G2A P14555 1/20 0.61
PLA2G4A P47712 1/20 0.61
TP53 P04637 4/20 0.61
CYP3A4 P08684 4/20 0.61
LMNA P02545 2/20 0.61
SMN1; SMN2 Q16637 2/20 0.61
MEN1 O00255 2/20 0.61
KMT2A Q03164 2/20 0.61
HPGD P15428 3/20 0.60
HSD17B10 Q99714 2/20 0.60
CALM1 P0DP23 1/20 0.60
PKM P14618 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25330135 0.92 MAPT (0.66) ABCB1ABCG2MAPTKDM4ENPC1
SCHEMBL4172232 0.91 MAPT (0.74) ABCB1ABCG2MAPTKDM4ENPC1
SCHEMBL21884870 0.88 MAPT (0.78) ABCB1ABCG2MAPTKDM4ENPC1
SCHEMBL13609779 0.88 ABCB1 (0.65) ABCB1ABCG2MAPTKDM4ENPC1
SCHEMBL28647882 0.86 ABCB1 (0.67) ABCB1ABCG2MAPTKDM4ENPC1
SCHEMBL21417969 0.86 MAPT (0.78) ABCB1ABCG2MAPTKDM4ENPC1
Acetic Acid SCHEMBL311830 0.86 TNKS (0.67) ABCB1ABCG2MAPTKDM4ENPC1
SCHEMBL311927 0.85 TNKS (0.71) ABCB1ABCG2MAPTKDM4ENPC1
SCHEMBL29887764 0.85 TNKS (0.71) ABCB1ABCG2MAPTKDM4ENPC1
SCHEMBL28639665 0.85 MAPT (0.82) ABCB1ABCG2MAPTKDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113512018-B Flavonoid compound and preparation method and application thereof 合肥工业大学 2023-07-18 CN disclosed
CN-113512018-A Flavonoid compound and preparation method and application thereof 合肥工业大学 2021-10-19 CN disclosed