⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL323191 | 0.75 | TNFSF11 (0.39) | — | |
| SCHEMBL10351391 | 0.74 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL3006414 | 0.71 | KDM4E (0.35) | — | |
| SCHEMBL4872430 | 0.71 | KDM4E (0.35) | — | |
| SCHEMBL3881061 | 0.71 | NOTUM (0.33) | — | |
| SCHEMBL143632 | 0.71 | KDM4E (0.46) | — | |
| SCHEMBL8762716 | 0.69 | — | — | |
| SCHEMBL10499576 | 0.69 | — | — | |
| SCHEMBL2904410 | 0.69 | POLB (0.38) | — | |
| SCHEMBL376967 | 0.69 | LCK (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1578741-B1 | AROMATIC COMPOUNDS AS ANTI-INFLAMMATORY, IMMUNOMODULATORY AND ANTI-PROLIFERATORY AGENTS | 4SC AG (DE) | 2011-07-13 | — | — | EP | claimed |
| EP-0078949-B1 | 1-FURYL-3,4-DIHYDROISOQUINOLINES, PROCESS FOR THEIR PREPARATION, THEIR USE AND MEDICINES CONTAINING THEM | BOEHRINGER INGELHEIM KG (DE) | 1985-06-19 | — | — | EP | claimed |
| EP-0078949-A1 | 1-Furyl-3,4-dihydroisoquinolines, process for their preparation, their use and medicines containing them | BOEHRINGER INGELHEIM KG (DE) | 1983-05-18 | — | — | EP | claimed |
| EP-0881262-B1 | Curable composition on the basis of polymers containing free carboxylic groups | VANTICO AG (CH) | 2003-11-19 | — | — | EP | disclosed |
| EP-0697440-B1 | Heat-hardenable composition, especially suited for use as automotive paints | VANTICO AG (CH) | 2001-11-14 | — | — | EP | disclosed |
| EP-0881262-A2 | Curable composition on the basis of polymers containing free carboxylic groups | Ciba SC Holding AG (CH) | 1998-12-02 | — | — | EP | disclosed |
| EP-0536085-B1 | Solid compositions based on polyglycidyl compounds having a molecular weight lower than 1500 | CIBA GEIGY AG (CH) | 1998-11-11 | — | — | EP | disclosed |
| EP-0697440-A2 | Heat-hardenable composition, especially suited for use as automotive paints | CIBA-GEIGY AG (CH) | 1996-02-21 | — | — | EP | disclosed |
| EP-0536085-A2 | Solid compositions based on polyglycidyl compounds having a molecular weight lower than 1500 | CIBA-GEIGY AG (CH) | 1993-04-07 | — | — | EP | disclosed |
| EP-0207396-B1 | TETRAHYDROFURANCARBOXYLIC-ACID DERIVATIVES | BASF Aktiengesellschaft (DE) | 1989-04-19 | — | — | EP | disclosed |
| EP-0207396-A1 | Tetrahydrofurancarboxylic-acid derivatives | BASF Aktiengesellschaft (DE) | 1987-01-07 | — | — | EP | disclosed |
| EP-0078949-B1 | 1-FURYL-3,4-DIHYDROISOQUINOLINES, PROCESS FOR THEIR PREPARATION, THEIR USE AND MEDICINES CONTAINING THEM | BOEHRINGER INGELHEIM KG (DE) | 1985-06-19 | — | — | EP | disclosed |
| EP-0078949-A1 | 1-Furyl-3,4-dihydroisoquinolines, process for their preparation, their use and medicines containing them | BOEHRINGER INGELHEIM KG (DE) | 1983-05-18 | — | — | EP | disclosed |
| EP-0078949-A1 | 1-Furyl-3,4-dihydroisoquinolines, process for their preparation, their use and medicines containing them | BOEHRINGER INGELHEIM KG (DE) | 1983-05-18 | — | — | EP | disclosed |