SCHEMBL21885570 — predicted protein targets

Predicted protein targets (top 20)

	gene	UniProt	supporting neighbours	confidence
▸	EGFR	P00533	8/20	0.51

▸	KDR	P35968	3/20	0.51

▸	SRC	P12931	2/20	0.51

▸	DRD2	P14416	1/20	0.51

▸	ERBB2	P04626	2/20	0.40

▸	PDGFRB	P09619	2/20	0.40

▸	PDGFRA	P16234	2/20	0.40

▸	RET	P07949	2/20	0.40

▸	PLK4	O00444	1/20	0.40

▸	GAK	O14976	1/20	0.40

▸	EPHB6	O15197	1/20	0.40

▸	RIPK2	O43353	1/20	0.40

▸	ERN1	O75460	1/20	0.40

▸	STK10	O94804	1/20	0.40

▸	MAP4K4	O95819	1/20	0.40

▸	CHEK2	O96017	1/20	0.40

▸	ABL1	P00519	1/20	0.40

▸	LCK	P06239	1/20	0.40

▸	FYN	P06241	1/20	0.40

▸	CSF1R	P07333	1/20	0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL21885568	0.86	EGFR (0.57)	EGFRKDRSRCDRD2ERBB2
SCHEMBL30364954	0.86	EGFR (0.57)	EGFRKDRSRCDRD2ERBB2
SCHEMBL30365096	0.83	KDR (0.59)	EGFRKDRSRCDRD2ERBB2
SCHEMBL21886113	0.83	KDR (0.59)	EGFRKDRSRCDRD2ERBB2
SCHEMBL30364938	0.83	KDR (0.59)	EGFRKDRSRCDRD2ERBB2
SCHEMBL21886111	0.83	KDR (0.59)	EGFRKDRSRCDRD2ERBB2
SCHEMBL21886100	0.83	KDR (0.59)	EGFRKDRSRCDRD2ERBB2
SCHEMBL21884858	0.81	KDR (0.51)	EGFRKDRSRCDRD2ERBB2
SCHEMBL21884874	0.77	EGFR (0.55)	EGFRKDRSRCDRD2ERBB2
SCHEMBL21884854	0.76	EGFR (0.52)	EGFRKDRSRCDRD2ERBB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2020057403-A1	INDOLE DERIVATIVE AND MEDICAL APPLICATION THEREOF	北京越之康泰生物医药科技有限公司	2020-03-26	—	—	WO	disclosed