⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20403014 | 0.72 | — | — | |
| SCHEMBL17059797 | 0.72 | — | — | |
| SCHEMBL1092118 | 0.67 | — | — | |
| SCHEMBL12474758 | 0.67 | GPR119 (0.34) | — | |
| SCHEMBL16321213 | 0.65 | GPR119 (0.48) | — | |
| SCHEMBL8533618 | 0.65 | — | — | |
| SCHEMBL23467550 | 0.65 | TSHR (0.39) | — | |
| SCHEMBL8188112 | 0.63 | — | — | |
| SCHEMBL23278505 | 0.63 | — | — | |
| SCHEMBL23132311 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020073011-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH APJ RECEPTOR ACTIVITY | ANNAPURNA BIO, INC. (US) | 2020-04-09 | — | — | WO | disclosed |