Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD5 | Q86SK9 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CCKAR | P32238 | 1/20 | 0.38 |
| ▸ | PRKDC | P78527 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.38 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27698610 | 0.92 | LMNA (0.48) | LMNATSHRMAPK1MEN1KMT2A | |
| SCHEMBL2186156 | 0.87 | LMNA (0.54) | SCD5LMNATSHRMAPK1MEN1 | |
| SCHEMBL2186823 | 0.84 | ADORA2A (0.46) | SCD5LMNATSHRMAPK1MEN1 | |
| SCHEMBL2186921 | 0.83 | MAPT (0.62) | LMNATSHRMAPK1MEN1KMT2A | |
| SCHEMBL2185672 | 0.81 | LMNA (0.53) | LMNATSHRMAPK1MEN1KMT2A | |
| SCHEMBL2186962 | 0.80 | LMNA (0.56) | LMNATSHRMAPK1MEN1KMT2A | |
| SCHEMBL2187717 | 0.79 | LMNA (0.53) | LMNATSHRMAPK1MEN1KMT2A | |
| SCHEMBL2187979 | 0.77 | MEN1 (0.55) | LMNATSHRMAPK1MEN1KMT2A | |
| SCHEMBL2187829 | 0.77 | POLB (0.48) | LMNATSHRMAPK1MEN1KMT2A | |
| SCHEMBL2186899 | 0.77 | ATM (0.48) | LMNATSHRMAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2343293-A1 | NOVEL PIPERIDIN-4-YL-THIAZOLE-CARBOXAMIDE ANALOGUES AS INHIBITORS OF T-CELL PROLIFERATION AND USES THEREOF | 4SC AG (DE) | 2011-07-13 | — | — | EP | disclosed |