Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 7/20 | 0.39 |
| ▸ | HTR5A | P47898 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | BRD2 | P25440 | 1/20 | 0.31 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.31 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.31 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12424595 | 0.77 | BRD4 (0.47) | BRD4HTR5AMAPK1PIK3CDBRD2 | |
| SCHEMBL23132786 | 0.77 | BRD4 (0.47) | BRD4HTR5AMAPK1PIK3CDBRD2 | |
| SCHEMBL21827039 | 0.76 | BRD4 (0.41) | BRD4HTR5ABRD2 | |
| SCHEMBL23868226 | 0.75 | ACACB (0.38) | ACACBKAT8 | |
| SCHEMBL8091841 | 0.73 | ACACB (0.42) | ACACB | |
| SCHEMBL19570437 | 0.73 | BRD4 (0.43) | BRD4HTR5AMAPK1PIK3CDBRD2 | |
| SCHEMBL16095176 | 0.72 | BRD4 (0.46) | BRD4HTR5AMAPK1PIK3CDBRD2 | |
| SCHEMBL16000112 | 0.71 | ACACB (0.38) | ACACB | |
| SCHEMBL16000131 | 0.70 | ACACB (0.38) | ACACB | |
| SCHEMBL21593760 | 0.70 | HTR5A (0.44) | BRD4HTR5AMAPK1PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020073011-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH APJ RECEPTOR ACTIVITY | ANNAPURNA BIO, INC. (US) | 2020-04-09 | — | — | WO | disclosed |